Palmitoyl tetrapeptide-20: the active ingredient known as Greyverse™

What is palmitoyl tetrapeptide-20?

Palmitoyl tetrapeptide-20 is a cosmetic peptide used in hair care serums for early grey hair. Peptides are short chains of amino acids that are used in cosmetics to support specific processes in the skin and scalp. Within the Neofollics Anti Grey product line, palmitoyl tetrapeptide-20 is used because of its role in processes related to hair pigmentation and hair condition. The ingredient is applied in a stable amide form, which makes it suitable for long-term use in leave-in products such as hair serums. Palmitoyl tetrapeptide-20 is not a colouring agent and does not dye the hair. Its action focuses on supporting the natural hair environment in which pigment processes take place.

Why is palmitoyl tetrapeptide-20 also called Greyverse™?

Palmitoyl tetrapeptide-20 is the INCI name of the ingredient. Greyverse™ is the commercial name used for this ingredient when it is applied within a specific cosmetic formulation. Greyverse™ is a registered trademark and refers to the same active substance.

Using more than one name for a single ingredient is common in cosmetics:

• the INCI name is used for clear and transparent labelling
• the technology name is used to explain the application and function

Greyverse™ does not refer to a different ingredient, but to the way palmitoyl tetrapeptide-20 is used in anti-grey hair care. At Neofollics, this technology is used in the Anti Grey Hair Serum as part of a broader cosmetic approach.

Palmitoyl tetrapeptide-20 and grey hair

Grey hair develops due to a gradual loss of pigment in the hair fibre. This process is influenced by genetic factors, age, and oxidative processes in the hair follicle. As the activity of pigment-producing cells decreases, the hair loses its natural colour.

Cosmetic hair care cannot stop or fully reverse this biological process. What cosmetics can do is support the conditions in which the hair and scalp function, especially in the early stages of greying.

Palmitoyl tetrapeptide-20 is used with this approach in mind. The ingredient focuses on processes related to hair pigmentation and hair condition, without making medical claims or promising the reversal of fully grey hair.

The role of palmitoyl tetrapeptide-20 in hair care

Palmitoyl tetrapeptide-20 is mainly used in hair serums. A serum is a suitable carrier for this type of ingredient because it allows long-lasting contact with the scalp and can be applied directly to the hair roots. At Neofollics, palmitoyl tetrapeptide-20 is included in the Anti Grey Hair Serum, a leave-in formula developed for daily and long-term use. The light texture allows consistent use without weighing the hair down, which suits people who want to care for early grey hair as part of their daily routine. By focusing on the scalp and hair roots, this application fits within cosmetic care aimed at maintaining hair condition and the overall appearance of the hair.

What does our clinical user study on Greyverse™ show?

Greyverse™ was evaluated in a clinical user study involving adults with early grey hair. In this study, a cosmetic formulation containing Greyverse™ was applied daily to the scalp over a period of several months. The study looked at changes in the visible appearance of the hair, including the visibility of grey hairs and the overall perception of hair colour. These changes were assessed using objective measurement methods and visual analysis.

After three months of use, a clearly noticeable change in hair appearance was observed. Measurements showed that the hair appeared darker and that grey hairs were less visible, especially in participants at an early stage of greying. This confirms that the ingredient is mainly suitable for cosmetic care for early grey hair. Based on these findings, Greyverse™ is used in the Neofollics Anti Grey Hair Serum.

This cosmetic serum is developed for long-term use and supports a well-groomed, natural hair appearance at the first signs of grey hair. Results may vary from person to person.